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Updated: Jul 31, 2025

A Revised Surgical Approach to Induce Endolymphatic Hydrops in the Guinea Pig
Published on: June 4, 2020
Lumpy, bumpy guinea pigs: a retrospective study of 619 biopsy samples of externally palpable masses submitted from
Melanie J Dobromylskyj1, Rebecca Hederer2, Ken C Smith2
1Finn Pathologists, One-Eyed Lane, Weybread, Diss, Norfolk IP21 5TT, UK; Pathobiology and Population Sciences, Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire AL9 7TA, UK.
Abstract:
Biopsy data on externally palpable masses in pet guinea pigs were retrieved from the archives of a large commercial pathology laboratory between November 2013 and July 2021. Of the 619 samples submitted from 493 animals, 54 (8.7%) had arisen from the mammary glands and 15 (2.4%) from the thyroid glands, with the remaining 550 (88.9%) involving the skin and subcutis, muscle (n = 1), salivary glands (n = 4), lips (n = 2), ears (n = 4) and peripheral lymph nodes (n = 23). Most of the samples were neoplastic, with 99 masses classified as epithelial in origin, 347 as mesenchymal, 23 as round cell, five as melanocytic and eight as unclassified malignant neoplasms. Lipomas were the most common neoplasm diagnosed, accounting for 286 of all samples submitted.

