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Bacterial Ocular Infections in Iran: A Systematic Review and Meta-analysis

Milad Shahini Shams Abadi1, Mohammad-Hassan Arjmand2, Farshad Kakian3

  • 1Cellular and Molecular Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran.

Oman Medical Journal
|May 3, 2023
PubMed
Abstract

Insights

Staphylococcus epidermidis is the most common bacterial cause of eye infections in Iran, found in 19.1% of cases. Other prevalent bacteria include Pseudomonas aeruginosa, Staphylococcus aureus, and viridans streptococci.

Area of Science:

  • Ophthalmology
  • Microbiology
  • Public Health

Background:

  • Eye infections are a significant health concern globally.
  • Common bacterial culprits include staphylococci, streptococci, and Pseudomonas aeruginosa.

Purpose of the Study:

  • To determine the prevalence of specific bacterial pathogens causing ocular infections in Iran.
  • To analyze the frequency of Staphylococcus aureus, Staphylococcus epidermidis, viridans group streptococci, and Pseudomonas aeruginosa.

Main Methods:

  • A systematic literature search was performed on major scientific databases (Web of Science, PubMed, Scopus, Embase).
  • Studies published by Iranian authors between January 2000 and December 2020 were included.
  • Meta-analysis was employed to synthesize prevalence data and assess publication bias.

Main Results:

  • Twenty-seven studies were included in the meta-analysis.
  • The prevalence of Staphylococcus epidermidis was 19.1% (95% CI: 12.5-28.1).
  • Prevalence estimates were 6.9% for Pseudomonas aeruginosa, 6.7% for Staphylococcus aureus, and 3.3% for viridans streptococci.

Conclusions:

  • Staphylococcus epidermidis is the predominant bacterial agent responsible for eye infections in Iran.
  • Understanding the prevalence of these pathogens is crucial for effective treatment and prevention strategies.
Keywords:
Eye InfectionsIranStaphylococcus aureusStaphylococcus epidermidisSystematic ReviewViridans Streptococci, Pseudomonas aeruginosa

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