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Laboratory methods: A concise review and update for COVID-19 diagnosis
Mohadeseh Nemati1, Ameneh Jafari2, Yaser Ebrahimi1
1Department of Clinical Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Cell Biochemistry and Function
|May 3, 2023
Summary
Accurate and early diagnosis of coronavirus disease 2019 (COVID-19) is crucial for controlling its spread. This review examines various COVID-19 detection methods, highlighting their pros and cons to improve diagnostic accuracy.
Area of Science:
- Virology
- Infectious Diseases
- Public Health
Background:
- The global outbreak of coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, necessitates effective diagnostic strategies.
- Early, safe, sensitive, and accurate detection of SARS-CoV-2 is vital for controlling transmission and enhancing public health surveillance.
Purpose of the Study:
- To review the progress of various diagnostic tools for COVID-19.
- To address the advantages and limitations of each detection method.
Main Methods:
- The review covers nucleic acid detection-based methods.
- It includes immunoassay-based, radiographic-based, and biosensor-based detection techniques.
Main Results:
- Various diagnostic methods for COVID-19 have been developed.
- Each method presents distinct advantages and limitations impacting diagnostic accuracy.
Conclusions:
- Improving diagnostic test limitations, particularly false-negative results, is essential.
- Further development of substantial COVID-19 diagnostic tests is required to improve patient outcomes and break transmission chains.
