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Renal transplantation in amyloidosis
Summary
Kidney transplantation in 12 amyloidosis patients showed that five survived one year post-transplant. Amyloid deposits were observed in two transplanted kidneys within three years.
Area of Science:
- Nephrology
- Transplantation Immunology
- Rheumatology
Background:
- Amyloidosis is a complex systemic disease characterized by extracellular deposition of misfolded proteins.
- Renal involvement is common in amyloidosis, often leading to end-stage renal disease.
- Kidney transplantation is a potential treatment option for selected patients with amyloidosis-related kidney failure.