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Updated: Jul 31, 2025

Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases

Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases

Published on: December 6, 2016

[Cerebral small vessel disease].

Leonardo Caranzano¹, Patrik Michel¹

¹Service de neurologie, Département des neurosciences cliniques, Centre hospitalier universitaire vaudois et Université de Lausanne, 1011 Lausanne.

Revue Medicale Suisse

|May 3, 2023

Summary

This summary is machine-generated.

Cerebral microangiopathy, a common cause of dementia, presents with varied symptoms despite similar imaging. Effective management focuses on controlling cerebrovascular risk factors.

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Last Updated: Jul 31, 2025

Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases

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A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage

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Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

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Published on: April 23, 2021

Area of Science:

Neurology
Vascular Neurology
Neuroscience

Context:

Cerebral microangiopathy is a significant contributor to dementia, second only to Alzheimer's disease.
It acts as a co-factor in most dementia cases.
Clinical presentations are diverse, encompassing cognitive, neuropsychiatric, gait, and urinary issues, alongside strokes.

Purpose:

To highlight the varied clinical manifestations of cerebral microangiopathy.
To emphasize the role of sub-radiological neurovascular unit damage in symptom variability.
To underscore the importance of managing cerebrovascular risk factors for prevention and treatment.

Summary:

Cerebral microangiopathy leads to diverse neurological deficits and strokes.
Damage to the neurovascular unit, often unseen on conventional MRI, contributes to variable patient outcomes.
Despite varied presentations, effective management and prevention strategies exist.

Impact:

Improved understanding of cerebral microangiopathy's complex clinical spectrum.
Highlights the need for advanced imaging or diagnostic approaches to assess neurovascular unit integrity.
Promotes aggressive management of cerebrovascular risk factors for dementia prevention and treatment.