[Preoperative 2-stage UHF-hyperthermia in combination with single-stage irradiation in breast cancer]

The authors described a method of two-stage UHF-hyperthermia combined with single irradiation of the breast prior to operation. At the 1st stage the temperature was 39 degrees C, duration of exposure 30 min directly before irradiation, irradiation at a dose of 13 Gy. The 2nd stage followed 2 h after irradiation, the temperature was 42 degrees C, duration 90 min. The above therapy did not deteriorate the conditions of surgical intervention, nor did it complicate a postoperative course. Local and general reactions were of transient nature. No recurrences were noted after 1 year of follow-up. A study of tumor pathomorphosis showed injuries of I degree in 30.8%, II degree in 46.2%, III degree in 5.6%, in single irradiation in 18, 8.4 and 2.8%, respectively.