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Updated: Jul 31, 2025

Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors
Published on: February 19, 2022
Jejunal gist simulating a uterine myoma: A case report
Maria Gonzalez-Vivo1, Ander Zugazaga2, Josep Maria Dedeu Cusco1
1Department of Gastroenterology, Hospital del Mar, Barcelona, Spain; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.
Diagnosing small bowel gastrointestinal stromal tumors (GISTs) causing bleeding is challenging. CT angiography proved most effective in identifying the bleeding source in this case, despite initial misdiagnosis.
Area of Science:
- Gastroenterology
- Oncology
- Radiology
Background:
- Small bowel gastrointestinal stromal tumors (GISTs) are rare neoplasms.
- Bleeding from GISTs presents a diagnostic challenge and can be life-threatening.
Observation:
- A 64-year-old woman presented with melena and anemia, initially unresponsive to standard endoscopic evaluations.
- Capsule endoscopy suggested a jejunal hemangioma, but subsequent imaging revealed a pelvic mass and suspected jejunal GIST with active bleeding.
Findings:
- Contrast-enhanced CT angiography successfully identified active bleeding from a jejunal GIST, a diagnosis missed by initial endoscopic procedures.
- Histopathology and immunohistochemical studies confirmed the jejunal GIST after surgical resection.
Implications:
- Bleeding in small bowel GISTs requires advanced imaging like CT angiography for accurate diagnosis.
- Delayed diagnosis of GISTs can lead to significant clinical management challenges.
- Bleeding is a prognostic indicator for GISTs, potentially related to tumor rupture and vascular invasion.
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