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Genotoxicity of gamma-irradiation in L5178Y mouse lymphoma cells
Mutation Research
|June 1, 1986
Abstract:
The ability of gamma-irradiation to induce gene mutation at the thymidine kinase locus and gross chromosome aberrations in L5178Y TK+/- 3.7.2C mouse lymphoma cells was evaluated. Positive results were obtained for both end-points. The majority of mutants were found to be small-colony mutants which correlated with the induction of gross chromosome aberrations.