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Carcinosarcoma: A Rare and Aggressive Breast Tumor in a Young Lady
Poh Nuan Leng1, Wan Zainira Wan Zain1,2, Mohd Azem Fathi Mohammad Azmi1,2
1Department of Surgery, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, MYS.
Abstract:
Carcinosarcoma of the breast is a subtype of metaplastic breast carcinoma characterized by differentiation of the neoplastic epithelium toward mesenchymal-looking elements. It is a highly aggressive rare subtype of invasive breast neoplasm that exhibits a distinct histologic entity. Only a limited number of reports related to this type of disease have been reported. Here, we present a case of breast carcinosarcoma in a lady in her early 20s, which is relatively young among all cases published. It was challenging to achieve diagnosis preoperatively with histopathological evaluation of the ultrasound-guided tru-cut biopsy sample. With no evidence of distant metastasis clinically and radiologically, a surgical option was opted for. Left mastectomy and left chest wall reconstruction with deep inferior epigastric artery free flap were performed. Post-excision specimen was confirmed to be carcinosarcoma.
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