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[Effect of total cholesterol level on platelet aggregation in patients with migraine]
In 34 women with simple migraine the total cholesterol concentration in the serum and the platelet aggregation index according to Wu and Hoak were determined. The blood cholesterol levels differed in them. Two groups of patients were isolated: group I with cholesterol level above the upper normal range and group II with cholesterol within this range. The mean concentration of this lipid differed significantly between these groups (p less than 0.001). The platelet aggregation index in group I was significantly lower than in the group with normal cholesterol level (p less than 0.05). During migraine attack a further fall was observed in the platelet aggregation index in the group with high cholesterol level (p less than 0.01). The authors suppose that cholesterol concentration may be one of the factors determining differences in platelet behaviour in migraine patients.
In 34 women with simple migraine the total cholesterol concentration in the serum and the platelet aggregation index according to Wu and Hoak were determined. The blood cholesterol levels differed in them. Two groups of patients were isolated: group I with cholesterol level above the upper normal range and group II with cholesterol within this range. The mean concentration of this lipid differed significantly between these groups (p less than 0.001). The platelet aggregation index in group I was significantly lower than in the group with normal cholesterol level (p less than 0.05). During migraine attack a further fall was observed in the platelet aggregation index in the group with high cholesterol level (p less than 0.01). The authors suppose that cholesterol concentration may be one of the factors determining differences in platelet behaviour in migraine patients.