An overview on COVID-19 and vaccines: findings and learnings from the pandemic

A S Binshaya1

  • 1Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, Alkharj, 11942, Saudi Arabia. abd.aldosari@psau.edu.sa.

Insights

This review details COVID-19

Area of Science:

  • Hematology
  • Virology
  • Immunology

Background:

  • The COVID-19 pandemic presents significant global health challenges.
  • Ongoing debates surround public health measures like mask mandates and vaccine passports.
  • Hematological complications are a notable aspect of COVID-19 disease.

Approach:

  • A comprehensive literature review was performed.
  • Keywords included "coronavirus disease", "COVID-19", "COVID-19 vaccinations", and "COVID-19 hematological complications".
  • Analysis focused on mutations in non-structural proteins NSP2 and NSP3.

Key Points:

  • COVID-19 is associated with various hematological issues, including coagulopathy and lymphopenia.
  • Changes in platelet counts, blood cell levels, and hemoglobin are frequently observed.
  • The review examines the impact of COVID-19 vaccination on hemolysis, multiple myeloma, and thrombocytopenia.

Conclusions:

  • Understanding COVID-19's hematological effects is crucial for patient management.
  • Vaccine development and their impact on hematological parameters require continued investigation.
  • Prevention and symptom management remain key clinical challenges during the pandemic.

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