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Coding-Complete Genome Sequences of G6P[14] Rotavirus Strain Detected in a Human Stool Specimen within the United

Mary C Casey-Moore1, Slavica Mijatovic-Rustempasic1, Jose Jaimes1

  • 1Viral Gastroenteritis Branch, Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Microbiology Resource Announcements
|May 4, 2023
PubMed

Insights

A novel rotavirus strain, G6P[14], was identified in a human stool sample in the United States. This finding expands the known diversity of rotavirus genotypes circulating in the region.

Area of Science:

  • Virology
  • Public Health

Background:

  • Rotavirus is a leading cause of severe diarrheal disease in infants and young children globally.
  • Surveillance of rotavirus strains is crucial for understanding epidemiology and vaccine effectiveness.

Purpose of the Study:

  • To report the detection and full genotype characterization of a rotavirus strain in the United States.
  • To contribute to the ongoing surveillance of rotavirus diversity.

Main Methods:

  • Detection of rotavirus in a human stool sample.
  • Full genome sequencing to determine the genotype constellation.

Main Results:

  • Identification of a G6P[14] rotavirus strain.
  • The complete genotype constellation was determined as G6-P[14]-I2-R2-C2-M2-A11-N2-T6-E2-H3.

Conclusions:

  • This is the first report of a G6P[14] rotavirus strain in the United States.
  • The presence of this strain highlights the need for continued molecular surveillance of rotavirus in the U.S.

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