Pilot protocol for the Parent and Infant Inter(X)action Intervention (PIXI) feasibility study

Area of Science:

• Developmental Pediatrics
• Genetics
• Family Support

Background:

• Infants with neurogenetic conditions (NGC) require early, specialized support.
• Caregiver involvement is crucial for infant development, especially with chronic conditions.
• Remote interventions offer accessible solutions for families facing geographical or logistical challenges.

Purpose of the Study:

• To detail the protocol for a pilot study on a novel early intervention program.
• To assess the feasibility, acceptability, and initial efficacy of the Parent and Infant Inter(X)action Intervention (PIXI).
• To evaluate a remotely delivered, two-phase intervention for infants diagnosed with NGC within their first year of life.

Main Methods:

• A non-randomized feasibility pilot study design.
• A year-long, virtually implemented intervention program.
• Two distinct intervention phases: psychoeducation/routines and targeted skill development.

Main Results:

• The study protocol is established for testing the PIXI intervention.
• Feasibility, acceptability, and initial efficacy of the remote intervention will be assessed.
• The intervention targets parents and infants with NGC diagnosed in the first year of life.

Conclusions:

• The PIXI intervention protocol provides a framework for supporting infants with NGC.
• Remote delivery is proposed as a feasible method for early intervention in NGC.
• Further research will determine the efficacy of PIXI in supporting infant development and caregiver well-being.