Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Examining Epilepsy in Angelman Syndrome: Insights From Caregiver-Reported Data in the Linking Angelman and Dup15q Data for Expanded Research Database.

Pediatric neurology·2026

Same author

The Intergenerational Impacts of Maternal Child Maltreatment on Adverse Neonatal Outcomes: Evidence From the I-CALM Study.

Child maltreatment·2026

Same author

A Systematic Process to Accurately Link Large-Scale Research Consents to State Public Health Newborn Screening Samples.

International journal of neonatal screening·2026

Same author

Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation.

Journal of medicinal chemistry·2026

Same author

Health care providers' perceptions of screening for risk of type 1 diabetes in newborns using genetic risk scores.

Journal of community genetics·2026

Same author

From Concerns to Care: Understanding Parental Priorities and Access to Early Intervention for Infants With Fragile X Syndrome.

Journal of intellectual disability research : JIDR·2026

Search research articles

Related Experiment Video

Updated: Jul 31, 2025

A Within-subjects Experimental Protocol to Assess the Effects of Social Input on Infant EEG

A Within-subjects Experimental Protocol to Assess the Effects of Social Input on Infant EEG

Published on: May 3, 2017

Pilot protocol for the Parent and Infant Inter(X)action Intervention (PIXI) feasibility study.

Anne C Wheeler¹, Katherine C Okoniewski¹, Samantha Scott¹

¹RTI International, Research Triangle Park, North Carolina, United States of America.

|May 4, 2023

Summary

This study outlines a remote early intervention for infants with neurogenetic conditions (NGC). The Parent and Infant Inter(X)action Intervention (PIXI) supports parents and infants through psychoeducation and targeted skill development.

More Related Videos

A Familiarization Protocol Facilitates the Participation of Children with ASD in Electrophysiological Research

A Familiarization Protocol Facilitates the Participation of Children with ASD in Electrophysiological Research

Published on: July 31, 2017

A Novel Experimental and Analytical Approach to the Multimodal Neural Decoding of Intent During Social Interaction in Freely-behaving Human Infants

A Novel Experimental and Analytical Approach to the Multimodal Neural Decoding of Intent During Social Interaction in Freely-behaving Human Infants

Published on: October 4, 2015

Related Experiment Videos

Last Updated: Jul 31, 2025

A Within-subjects Experimental Protocol to Assess the Effects of Social Input on Infant EEG

A Within-subjects Experimental Protocol to Assess the Effects of Social Input on Infant EEG

Published on: May 3, 2017

A Familiarization Protocol Facilitates the Participation of Children with ASD in Electrophysiological Research

A Familiarization Protocol Facilitates the Participation of Children with ASD in Electrophysiological Research

Published on: July 31, 2017

A Novel Experimental and Analytical Approach to the Multimodal Neural Decoding of Intent During Social Interaction in Freely-behaving Human Infants

A Novel Experimental and Analytical Approach to the Multimodal Neural Decoding of Intent During Social Interaction in Freely-behaving Human Infants

Published on: October 4, 2015

Area of Science:

Developmental Pediatrics
Genetics
Family Support

Background:

Infants with neurogenetic conditions (NGC) require early, specialized support.
Caregiver involvement is crucial for infant development, especially with chronic conditions.
Remote interventions offer accessible solutions for families facing geographical or logistical challenges.

Purpose of the Study:

To detail the protocol for a pilot study on a novel early intervention program.
To assess the feasibility, acceptability, and initial efficacy of the Parent and Infant Inter(X)action Intervention (PIXI).
To evaluate a remotely delivered, two-phase intervention for infants diagnosed with NGC within their first year of life.

Main Methods:

A non-randomized feasibility pilot study design.
A year-long, virtually implemented intervention program.
Two distinct intervention phases: psychoeducation/routines and targeted skill development.

Main Results:

The study protocol is established for testing the PIXI intervention.
Feasibility, acceptability, and initial efficacy of the remote intervention will be assessed.
The intervention targets parents and infants with NGC diagnosed in the first year of life.

Conclusions:

The PIXI intervention protocol provides a framework for supporting infants with NGC.
Remote delivery is proposed as a feasible method for early intervention in NGC.
Further research will determine the efficacy of PIXI in supporting infant development and caregiver well-being.