Rhabdomyolysis After Intravenous Iron Sucrose Infusion During Pregnancy.

Area of Science:

• Obstetrics and Gynecology
• Hematology
• Nephrology

Background:

• Iron deficiency anemia is common during pregnancy.
• Intravenous (IV) iron infusions are frequently used for treatment.
• While generally safe, adverse reactions to IV iron can occur.

Purpose of the Study:

• To report a case of rhabdomyolysis in a pregnant patient receiving IV iron sucrose.
• To highlight the potential association between IV iron infusion and rhabdomyolysis during pregnancy.

Main Methods:

• A case study of a pregnant patient diagnosed with rhabdomyolysis.
• Monitoring of clinical symptoms and laboratory values (creatine kinase, electrolytes).
• Treatment with intravenous fluids and electrolyte repletion.

Main Results:

• The patient developed rhabdomyolysis after a second dose of IV iron sucrose at 32 6/7 weeks gestation.
• Initial lab results showed elevated creatine kinase (2,437 U/L) and low potassium (2.1 mEq/L).
• Symptoms improved within 48 hours of treatment, and creatine kinase normalized within one week post-discharge.

Conclusions:

• Rhabdomyolysis is a potential adverse reaction associated with IV iron infusions during pregnancy.
• Early recognition and management are crucial for favorable outcomes.
• This case underscores the importance of monitoring for rare but serious complications.