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Updated: Jul 31, 2025

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Life-threatening complication: the development of necrotising fasciitis in a preterm neonate with omphalitis
Maira Jamal1, Kanza Ateeque2, Maida Binte Khalid Quddusi3
1Pediatrics, Hamdard University College of Medicine and Dentistry, Karachi, Sindh, Pakistan.
Abstract:
Omphalitis is a mild medical condition that can turn severe in exceptional situations leading to necrotising fasciitis. The most common cause of omphalitis is umbilical vein catheterisation (UVC) where the cleanliness measures can be compromised. The treatment options for omphalitis include antibiotics, debridement and supportive care. Sadly, the fatality rate in such cases is high. This report is about a premature female baby who was admitted to a neonatal intensive care unit after her birth at 34 weeks of gestation. UVC was performed on her which led to abnormal changes in the skin around her umbilicus. Further tests revealed that she had omphalitis and was treated with antibiotics and supportive care. Unfortunately, her condition quickly worsened and she was diagnosed with necrotising fasciitis which ultimately resulted in her death. This report provides details about the patient's symptoms, course of illness and treatment for necrotising fasciitis.
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