Fluoroquinolone-Induced Sweet Syndrome: A Case Report

Area of Science:

• Dermatology
• Immunology
• Pathology

Background:

• Sweet syndrome (SS) is a rare non-vasculitic neutrophilic dermatosis.
• Characterized by fever, tender erythematous plaques/nodules, and neutrophilic infiltrates.
• Often presents with systemic manifestations due to immune-mediated hypersensitivity.

Observation:

• A case of Sweet syndrome in a 55-year-old female in Pakistan is presented.
• The patient experienced sudden onset of tender plaques and nodules with fever.
• Diagnosis was confirmed through thorough investigations.

Findings:

• The case highlights the rarity of Sweet syndrome in the reported region.
• Skin biopsy revealed dense neutrophilic infiltrates, consistent with SS.
• The patient responded well to corticosteroid therapy.

Implications:

• This case contributes to the understanding of Sweet syndrome's presentation in diverse geographical locations.
• Highlights the importance of prompt diagnosis and corticosteroid treatment for SS.
• Emphasizes the need for increased awareness of rare dermatological conditions in Pakistan.