Biological Therapy for Avascular Necrosis of Femoral Head - A Case Report
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Updated: Jul 31, 2025

Augmented Reality Navigation-Guided Core Decompression for Osteonecrosis of Femoral Head
Published on: April 12, 2022
A Navaladi Shankar1, Tarun Jayakumar2, N Giri Pranav3
1Department of Orthopaedics, Apollo Hospitals, Greams Road, Chennai, Tamil Nadu, India.
Introduction:
Avascular necrosis (AVN) of the femoral head is a type of osteonecrosis with the disruption of blood supply to the head of the femur. Management of AVN femoral head depends on the stage of the disease. In this case report, we elaborated on the biological therapy for bilateral AVN of the femoral head.
Case Report:
A 44-year-old male presented with pain in both hips for 2 years with a history of rest pain in both hips. Radiologically, the patient was diagnosed with bilateral AVN of the femoral head. The patient was offered bone marrow aspirate concentrate (BMAC) in the right femoral head, followed up for 7 years, whereas the adult autologous live cultured osteoblasts in the left femoral head, followed up for 6 years.
Conclusion:
Biological therapy with differentiated osteoblasts remains a viable option for AVN femoral head when compared with an undifferentiated BMAC cocktail.

