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A Practical Guide to Phylogenetics for Nonexperts
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Tree Visualization By One Table (tvBOT): a web application for visualizing, modifying and annotating phylogenetic

Jianmin Xie1,2, Yuerong Chen1,2, Guanjing Cai1,2

  • 1Guangdong Provincial Key Laboratory of Marine Biotechnology, Shantou University, Shantou 515063, China.

Nucleic Acids Research
|May 5, 2023
PubMed
Summary

tvBOT is a web application for visualizing and annotating phylogenetic trees efficiently. It simplifies data preparation and offers real-time, interactive style adjustments for diverse annotation types.

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Area of Science:

  • Bioinformatics
  • Computational Biology
  • Data Visualization

Background:

  • Phylogenetic tree visualization and annotation are crucial in evolutionary biology.
  • Existing tools often require complex data formatting and lack interactive features.
  • Efficiently integrating diverse annotation data with tree structures remains a challenge.

Purpose of the Study:

  • To develop a user-friendly and efficient web application, tvBOT, for phylogenetic tree visualization and annotation.
  • To streamline the process of data preparation and annotation layer management.
  • To provide real-time, interactive style adjustments and flexible export options for phylogenetic trees.

Main Methods:

  • tvBOT utilizes a data-driven engine for annotations, requiring uniformly formatted data in a single table.
  • A layer manager facilitates the addition and management of annotation dataset layers.
  • The application features a real-time display engine for immediate visual feedback on style adjustments.
  • It supports 26 annotation dataset types and offers export in publication-ready formats and JSON.

Main Results:

  • tvBOT enables efficient data preparation without redundant style and syntax data.
  • Users can manage annotation layers and apply diverse, real-time style adjustments via an interactive interface.
  • The application supports the combination of 26 annotation types for comprehensive tree representation.
  • Export options include publication-ready graphics and JSON for sharing, re-editing, or template creation.

Conclusions:

  • tvBOT provides an efficient, user-friendly platform for phylogenetic tree visualization and annotation.
  • Its data-driven approach and real-time interactive features simplify complex annotation tasks.
  • The application enhances the reusability and shareability of phylogenetic data and visualizations.