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Long non‑coding RNAs in multiple myeloma (Review).

Chenbo Yang1, Yinghao Liang2, Jiao Shu1

  • 1Department of Pathology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.

International Journal of Oncology
|May 5, 2023
PubMed
Summary

Long non-coding RNAs (lncRNAs) are key regulators in multiple myeloma (MM), a blood cancer. Understanding lncRNAs offers new pathways for MM diagnosis and treatment.

Keywords:
drug resistancelong non‑coding RNAmolecular mechanismmultiple myelomaprognosistumor progression

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Area of Science:

  • Hematology
  • Oncology
  • Molecular Biology

Background:

  • Multiple myeloma (MM) is a significant hematological malignancy affecting middle-aged and older adults.
  • MM is characterized by drug resistance and high recurrence rates, posing serious health challenges.
  • Long non-coding RNAs (lncRNAs) are emerging regulators of cancer, including MM.

Conclusions:

  • lncRNAs are crucial in the development and progression of multiple myeloma.
  • Targeting specific lncRNAs presents a promising avenue for novel MM therapies.
  • Further research into lncRNAs can lead to improved diagnostic tools and treatment strategies for MM patients.