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Updated: Jul 31, 2025

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Synthesis and structures of homoleptic germylenes and stannylenes with sulfonimidamide ligands
Nicolas Lentz1, Alexandre Sodreau1, Alejandra Acuña1,2
1Université de Toulouse, UPS, LHFA (Laboratoire Hétérochimie Fondamentale et Appliquée), UMR/CNRS 5069, 118 route de Narbonne, 31062 Toulouse Cedex 09, France. david.madec@univ-tlse3.fr.
Abstract:
An unusual series of germylenes and stannylenes with homoleptic symmetric and unsymmetric N-substituted sulfonimidamide ligands PhSO(NiPr)(NHiPr) 1 and PhSO(NMes)(NHiPr) 2 have been prepared by protonolysis reaction of Lappert's metallylenes [M(HMDS)2] (M = Ge or Sn) with two equivalents of the appropriate sulfonimidamide. The homoleptic germylenes [PhSO(NiPr)2]2Ge 3 and [PhSO(NMes)(NiPr)]2Ge 4, and stannylenes [PhSO(NiPr)2]2Sn 5 and [PhSO(NMes)(NiPr)]2Sn 6 were fully characterized by NMR spectroscopy and by X-ray diffraction analysis. DFT calculations have been performed to understand the electronic properties brought by the sulfonimidamide ligand.
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