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The severity of COVID-19 across the spectrum of HIV

Kathleen W Miller1, Rajesh T Gandhi

  • 1Department of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts, USA.

Current Opinion in HIV and AIDS
|May 5, 2023
PubMed

Insights

HIV infection is an independent risk factor for severe COVID-19, especially with low CD4 counts. This underscores the importance of diagnosing and treating HIV and vaccinating people with HIV against COVID-19.

Area of Science:

  • Infectious Diseases
  • Public Health
  • Immunology

Background:

  • The COVID-19 pandemic has disproportionately affected vulnerable populations.
  • People with HIV (PWH) face unique challenges due to comorbidities and social determinants of health.
  • Early research on HIV and COVID-19 severity yielded mixed results.

Conclusions:

  • HIV infection independently increases the risk of severe COVID-19.
  • Effective management of HIV and COVID-19 requires addressing comorbidities and social determinants.
  • Prompt HIV diagnosis, treatment, and COVID-19 vaccination/treatment are crucial for PWH.
Abstract

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