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Updated: Jul 31, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Secukinumab for the treatment of generalized pustular psoriasis: A case report
Introduction:
Generalized pustular psoriasis (GPP) is a rare subtype of psoriasis that manifests as a generalized pustular eruption.
Patient Concerns:
A 31-year-old female was admitted to the hospital in June 2021 with a widespread erythematous, itchy, and scaly rash for a week. The patient has a 10-year history of psoriasis vulgaris.
Diagnosis:
GPP complicated by a late-stage viral infection and early-stage renal damage.
Interventions:
Weekly subcutaneous injections of 300 mg of secukinumab for a month, followed by monthly (every 4 weeks) injections of 300 mg of secukinumab for 20 weeks.
Outcomes:
The symptoms of pustules and erythema were reduced, and the patient reported pain relief soon after the first injection. The patient had no serious adverse reactions during treatment and follow-up.
Conclusions:
Secukinumab might be an optional treatment strategy for GPP.

