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An Iodine Balance Study in Chinese School-age Children
Wenxing Guo1, Ying Yang1, Wen Jiang2
1Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin 300070, China.
Context:
Few iodine balance studies have been conducted in school-age children.
Objective:
This study aimed to conduct an iodine balance study in school-age children.
Methods:
We measured daily iodine intake, excretion, and retention for 3 consecutive days without any dietary interventions in school-age children. Linear mixed-effects models were used to fit the relationship between total iodine intake and iodine retention.
Results:
29 children aged 7-12 years (mean age 10.2 ± 1.4 years) with normal thyroid function and thyroid volume were recruited. The 0 balance value (iodine intake = iodine excretion, iodine retention = 0 μg/day) shifted with iodine intake in an iodine sufficient population. The 0 balance value for school-age children with an iodine intake of 235 (133, 401) μg/day is 164 μg/day. Children aged 7-12 years with iodine intake >400 μg/day were almost all in a positive iodine state.
Conclusion:
An iodine intake of 235 (133, 401) μg/day for children aged 7-10 years achieved a 0 balance value of 164 μg/day. Long-term iodine intake of >400 μg/day is not recommended.
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