Equitable Access to Clinical Trials: How Do We Achieve It?

Ana Acuña-Villaorduña1, Joaquina Celebre Baranda2, Jessica Boehmer3

  • 1Cancer Immunotherapy Program, Tisch Cancer Institute, Mount Sinai School of Medicine, New York, NY.

Insights

Improving oncology clinical trial diversity is crucial. Strategies include broader eligibility, simplified procedures, community outreach, telehealth, and financial support to ensure equitable cancer research participation.

Area of Science:

  • Oncology
  • Clinical Trials
  • Health Equity

Background:

  • Significant disparities exist between oncology clinical trial participants and the general cancer patient population.
  • This mismatch hinders the generalizability of trial findings and perpetuates health inequities.

Purpose of the Study:

  • To highlight the urgent need for diverse patient accrual in oncology clinical trials.
  • To outline current strategies and best practices aimed at increasing participation of underserved populations.

Main Methods:

  • Review of current initiatives and best practices for enhancing diversity in clinical trials.
  • Emphasis on regulatory mandates for equity and inclusivity.

Main Results:

  • Effective strategies include broadening eligibility criteria, simplifying trial processes, and implementing community outreach programs.
  • Decentralization of trial procedures, use of telehealth, and financial assistance for participants are also key.

Conclusions:

  • Achieving substantial improvement in diversity requires significant cultural shifts across educational, professional, research, and regulatory sectors.
  • Increased public, corporate, and philanthropic funding is essential to support these changes and ensure equitable cancer research.

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