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Naftidrofuryl-induced acute hepatic necrosis
Postgraduate Medical Journal
|April 1, 1986
Summary
A 60-year-old woman developed acute hepatic necrosis after five months of naftidrofuryl treatment. This case highlights a potential severe adverse drug reaction to naftidrofuryl affecting the liver.
Area of Science:
- Hepatology
- Pharmacology
- Toxicology
Background:
- Naftidrofuryl is a vasoactive drug used for peripheral arterial disease.
- Drug-induced liver injury (DILI) is a significant clinical concern.
- The spectrum of hepatic adverse events associated with naftidrofuryl requires further characterization.