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Related Concept Videos

Hardy-Weinberg Principle01:49

Hardy-Weinberg Principle

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Diploid organisms have two alleles of each gene, one from each parent, in their somatic cells. Therefore, each individual contributes two alleles to the gene pool of the population. The gene pool of a population is the sum of every allele of all genes within that population and has some degree of variation. Genetic variation is typically expressed as a relative frequency, which is the percentage of the total population that has a given allele, genotype or phenotype.
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Mutation, Gene Flow, and Genetic Drift01:09

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In a population that is not at Hardy-Weinberg equilibrium, the frequency of alleles changes over time. Therefore, any deviations from the five conditions of Hardy-Weinberg equilibrium can alter the genetic variation of a given population. Conditions that change the genetic variability of a population include mutations, natural selection, non-random mating, gene flow, and genetic drift (small population size).
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Conservation of Small Populations02:04

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Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...
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What is Population Genetics?01:25

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A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
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Conservation of Declining Populations02:07

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Conservation of declining population focuses on ways of detecting, diagnosing, and halting a population decline. The approach uses methods to prevent populations from going extinct.
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Genetic Drift03:33

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Natural selection—probably the most well-known evolutionary mechanism—increases the prevalence of traits that enhance survival and reproduction. However, evolution does not merely propagate favorable traits, nor does it always benefit populations.
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Related Experiment Video

Updated: Jul 31, 2025

Simultaneous Assessment of Kinship, Division Number, and Phenotype via Flow Cytometry for Hematopoietic Stem and Progenitor Cells
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Stable populations and Hardy-Weinberg equilibrium.

Alan E Stark1,2

  • 1School of Mathematics and Statistics FO7, The University of Sydney, Sydney, NSW, 2006, Australia. alans@exemail.com.au.

Hereditas
|May 5, 2023
PubMed
Summary

This study reveals conditions for maintaining Hardy-Weinberg proportions despite non-random mating at an autosomal locus with five alleles. It challenges the assumption of random mating in population genetics.

Area of Science:

  • Population genetics
  • Mathematical biology
  • Evolutionary genetics

Background:

  • Hardy-Weinberg equilibrium is a foundational concept in population genetics.
Keywords:
Autosomal locusFive allelesHardy-Weinberg lawNon-random mating

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  • It typically assumes random mating, which is often unrealistic in natural populations.
  • Understanding deviations from equilibrium is crucial for studying evolutionary processes.