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Biological therapy for severe asthma - Indian perspectives and challenges
Rajesh Venkitakrishnan1, Jolsana Augustine2, Divya Ramachandran2
1Senior Consultant and Head of Department, Rajagiri Hospital, Kochi, Kerala, India.
Summary
Monoclonal antibodies offer significant benefits for severe asthma patients in India. This review guides clinicians on selecting the optimal biological therapy amidst unique healthcare challenges and patient perspectives.
Area of Science:
- Pulmonology
- Immunology
- Pharmacology
Background:
- Asthma is a heterogeneous respiratory condition with severe cases consuming significant healthcare resources.
- Severe asthma disproportionately impacts healthcare utilization despite representing a minority of patients.
- Monoclonal antibodies have emerged as effective treatments for selected severe asthma patients.
Purpose of the Study:
- To review available monoclonal antibodies for severe asthma treatment in India.
- To explore Indian patients' perspectives on biological therapies.
- To identify challenges and provide practical guidance for monoclonal antibody use in India.
Main Methods:
- Literature review of monoclonal antibodies for asthma.
- Analysis of the Indian healthcare context for biologicals.
- Synthesis of patient and physician perspectives on biologic therapy.
Main Results:
- Monoclonal antibodies show promise for severe asthma in India.
- Unique patient attitudes and healthcare budget allocations influence biologic therapy access.
- Challenges exist in selecting optimal agents and managing patient expectations.
Conclusions:
- Optimizing monoclonal antibody selection requires understanding the Indian clinical and economic landscape.
- Addressing patient and physician challenges is crucial for successful biologic therapy implementation.
- Further research and practical guidelines are needed for effective severe asthma management in India.
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