Related Experiment Video
Updated: Jul 31, 2025
07:50
A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
16.0K
Pediatric Brucellosis: A Challenging Diagnosis-Case Report
Areeba Shaikh1, Munira Sarfaraz1, Shaista Ehsan1
1Dr Ziauddin Hospital Clifton Karachi, Karāchi, Sindh, Pakistan.
Journal of Primary Care & Community Health
|May 6, 2023
Summary
This study highlights pediatric brucellosis in Pakistan, a widespread zoonotic disease. Early diagnosis and appropriate antimicrobial treatment, including doxycycline and rifampicin, are crucial for symptom improvement in children.
Area of Science:
- Infectious Diseases
- Pediatric Medicine
- Public Health
Background:
- Brucellosis is a significant zoonotic disease with limited literature in Pakistan, potentially causing diagnostic delays.
- This study addresses the gap by focusing on pediatric brucellosis, detailing its epidemiology, clinical presentation, and treatment outcomes.
- Understanding brucellosis in children is vital for public health initiatives in endemic regions.
Observation:
- An 11-year-old child presented with prolonged abdominal pain and fever.
- Abdominal ultrasound revealed hepato-splenomegaly and pleural effusion.
- Diagnostic workup, including antibody tests, confirmed brucellosis.
Findings:
- The child received a three-month course of doxycycline, rifampin, and trimethoprim-sulfamethoxazole.
- Treatment was continued with oral doxycycline and rifampicin for five weeks.
- Significant symptom improvement was observed by the end of the treatment regimen.
Implications:
- Brucellosis requires prompt diagnosis and multi-drug antimicrobial therapy, considering the intracellular nature of *Brucella*.
- Treatment protocols may need adjustment based on patient age and clinical complications.
- This case contributes valuable data to the understanding of pediatric brucellosis management.
Related Concept Videos
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
22
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
22
01:26Pulmonary Tuberculosis IV
182
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
182