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Updated: Jul 31, 2025
Author Spotlight: Recent Advancements in Reoperative Foregut Surgery
Published on: September 22, 2023
Swallowing outcomes over time after total pharyngolaryngectomy and free flap reconstruction
Roxane Elaldi1, Philippe Gorphe1, Frederic Kolb2
1Gustave Roussy, Paris-Saclay University, Department of Head and neck Oncology, Villejuif F-94805, France.
Background:
One of the challenges after total pharyngolaryngectomy (TPL) is to restore the swallowing function. The aim of this study was to compare swallowing outcomes between patients who underwent reconstruction with jejunum free flap (JFF) and other free flaps (OFFs).
Methods:
This retrospective study included patients who underwent TPL and free flap reconstruction. The endpoints were the evolution of swallowing outcomes during the first five years after treatment assessed by the Functional Oral Intake Scale (FOIS), and outcomes associated with complications.
Results:
One hundred and eleven patients were included, 84 patients in the JFF group and 27 in the OFF group. The patients in the OFF group experienced more chronic pharyngostoma (p = 0.001) and pharyngoesophageal stricture (p = 0.008). During the first year, a lower FOIS score tended to be associated with OFF (p = 0.137), and this result remained stable over time.
Conclusions:
This study suggests that JFF reconstruction provides better swallowing outcomes than OFF reconstruction, stable over time.
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