Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Rh Blood Group01:19

Rh Blood Group

1.6K
The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
1.6K
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

373
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
373
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

1.0K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
1.0K
Transcytosis of IgG01:15

Transcytosis of IgG

2.8K
Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
2.8K
Mitral Valve Prolapse III: Nursing Management01:19

Mitral Valve Prolapse III: Nursing Management

21
The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
21
Development of Immunocompetence01:22

Development of Immunocompetence

379
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
379

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to 'Society for Maternal-Fetal Medicine Consult Series #69: Hepatitis B in Pregnancy: Updated Guidelines' [American Journal of Obstetrics and Gynecology 230/4 (2024) B2-B11].

American journal of obstetrics and gynecology·2026
Same author

Does magnesium sulfate affect duration of labor for nulliparous patients undergoing induction of labor for hypertensive disorders of pregnancy at term?<sup></sup>

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·2026
Same author

Factors affecting success of vaginal delivery in nulliparous patients receiving magnesium sulfate during labor induction.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·2025
Same author

Trends in Perinatal Group B Streptococcal Disease After Updated Screening Recommendations in the United States.

O&G open·2025
Same author

The new frontier: a case for whole exome sequencing with multiple fetal anomalies.

Case reports in perinatal medicine·2025
Same author

Clinical and demographic factors associated with increased risk of postpartum readmission among patients presenting to the emergency department by 6 weeks postpartum.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·2025
Same journal

Bridging Science and Practice in Gender-Affirming Care: A Compendium for Gynecologists.

Obstetrics and gynecology clinics of North America·2026
Same journal

Evidence, Clinical Expertise, and Research Gaps in Gender-Affirming Care.

Obstetrics and gynecology clinics of North America·2026
Same journal

Evaluation and Management of the Pediatric Gender-Diverse Patient.

Obstetrics and gynecology clinics of North America·2026
Same journal

Expanding Access to Cervical Cancer Screening for Transgender and Nonbinary Individuals.

Obstetrics and gynecology clinics of North America·2026
Same journal

Updates on Breast Cancer Screening and Special Considerations for Transgender Men and Women.

Obstetrics and gynecology clinics of North America·2026
Same journal

Contraceptive Needs of the Transmasculine Patient.

Obstetrics and gynecology clinics of North America·2026
See all related articles

Related Experiment Video

Updated: Jul 31, 2025

A Murine Model of Group B Streptococcus Vaginal Colonization
10:19

A Murine Model of Group B Streptococcus Vaginal Colonization

Published on: November 16, 2016

14.5K

Group B Streptococcus in Pregnancy.

Jenny Y Mei1, Neil S Silverman1

  • 1Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, 200 Medical Plaza, Suite 430, Los Angeles, CA 90095-1740, USA.

Obstetrics and Gynecology Clinics of North America
|May 6, 2023
PubMed
Summary
This summary is machine-generated.

Preventing early-onset neonatal sepsis from group B streptococcus (GBS) involves screening pregnant patients and administering intrapartum antibiotic prophylaxis (IAP) when indicated. Prompt IAP significantly reduces GBS transmission risks to newborns.

Keywords:
Group B streptococcusIntrapartum antibiotic prophylaxisNeonatal sepsis

More Related Videos

Human Placental and Decidual Organ Cultures to Study Infections at the Maternal-fetal Interface
07:04

Human Placental and Decidual Organ Cultures to Study Infections at the Maternal-fetal Interface

Published on: July 21, 2016

21.0K
Models of Murine Vaginal Colonization by Anaerobically Grown Bacteria
08:53

Models of Murine Vaginal Colonization by Anaerobically Grown Bacteria

Published on: May 25, 2022

3.9K

Related Experiment Videos

Last Updated: Jul 31, 2025

A Murine Model of Group B Streptococcus Vaginal Colonization
10:19

A Murine Model of Group B Streptococcus Vaginal Colonization

Published on: November 16, 2016

14.5K
Human Placental and Decidual Organ Cultures to Study Infections at the Maternal-fetal Interface
07:04

Human Placental and Decidual Organ Cultures to Study Infections at the Maternal-fetal Interface

Published on: July 21, 2016

21.0K
Models of Murine Vaginal Colonization by Anaerobically Grown Bacteria
08:53

Models of Murine Vaginal Colonization by Anaerobically Grown Bacteria

Published on: May 25, 2022

3.9K

Area of Science:

  • Obstetrics and Gynecology
  • Neonatal Medicine
  • Infectious Disease

Background:

  • Group B Streptococcus (GBS) poses a significant risk for early-onset neonatal sepsis.
  • Effective prevention strategies are crucial for improving neonatal outcomes.

Purpose of the Study:

  • To outline screening and management guidelines for GBS in pregnant patients.
  • To reduce the incidence of early-onset neonatal sepsis caused by GBS.

Main Methods:

  • Screening pregnant patients for GBS colonization between 36 0/7 and 37 6/7 weeks' gestation.
  • Administering intrapartum antibiotic prophylaxis (IAP) for positive cultures, GBS bacteriuria, or history of GBS disease in a newborn.
  • Providing IAP based on intrapartum risk factors when GBS status is unknown.

Main Results:

  • Timely screening identifies GBS carriers eligible for IAP.
  • IAP administration in indicated cases significantly lowers the risk of neonatal GBS sepsis.
  • Adherence to guidelines ensures appropriate antibiotic use during labor.

Conclusions:

  • Universal GBS screening and targeted IAP are effective in preventing early-onset neonatal sepsis.
  • Intrapartum management protocols should be followed to minimize GBS transmission.
  • Penicillin is the preferred agent for IAP, with alternatives available for allergic patients.