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Updated: Jul 31, 2025

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
Malignant and Nonmalignant Sinonasal Tumors
Natalya Nagornaya1, Gaurav Saigal1, Rita Bhatia1
1Department of Radiology, University of Miami Miller School of Medicine, Jackson Memorial Hospital, 1611 NW12th Avenue, WW- 279, Miami, FL 33136, USA.
Sinonasal tumors are rare and complex. This review covers their classification and imaging features on CT and MR, aiding radiologists in diagnosis and treatment planning for these challenging nasal and paranasal masses.
Area of Science:
- Radiology
- Oncology
- Pathology
Background:
- Sinonasal tumors are rare, diverse, and complex lesions.
- Malignant sinonasal tumors have a grave prognosis and require biopsy for diagnosis.
Purpose of the Study:
- To review the classification of sinonasal tumors.
- To provide imaging examples and characteristics of clinically important nasal and paranasal masses.
- To aid radiologists in narrowing differential diagnoses and planning treatment.
Main Methods:
- Review of sinonasal tumor classification.
- Presentation of CT and MR imaging examples and characteristics.
- Discussion of imaging findings for differential diagnosis.
Main Results:
- Sinonasal tumors exhibit diverse and overlapping imaging features.
- No single imaging feature is pathognomonic for specific sinonasal tumors.
- Radiologists' knowledge of CT and MR findings is crucial for diagnosis.
Conclusions:
- Accurate diagnosis and mapping of sinonasal tumors are essential for effective treatment planning.
- Comprehensive understanding of imaging findings assists in differentiating various nasal and paranasal masses.
- Early diagnosis through imaging interpretation improves patient outcomes for sinonasal malignancies.
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