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The Effect of Prone Positioning After Lung Transplantation
Anna Elisabeth Frick1, Judith Schiefer2, Mathias Maleczek2
1Department of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.
The Annals of Thoracic Surgery
|May 7, 2023
Summary
Prone positioning improved lung compliance and oxygenation in lung transplant recipients. This therapy shows potential benefits for post-transplant recovery and gas exchange.
Area of Science:
- Cardiology
- Pulmonary Medicine
- Transplant Surgery
Background:
- Prone positioning is standard for acute respiratory distress syndrome.
- Its use in lung transplant recipients is not well-established.
- This study examines prone positioning's impact on lung transplant outcomes.
Purpose of the Study:
- To investigate the efficacy of prone positioning in improving gas exchange after lung transplantation.
- To assess the impact on early outcomes and survival in lung transplant recipients.
Main Methods:
- Analysis of clinical data from 583 lung transplant recipients.
- Prone positioning applied for impaired gas exchange, edema, or reperfusion injury.
- Comparison of outcomes between prone (n=165) and supine (n=418) positioned patients.
Main Results:
- Prone patients had lower initial oxygenation and lung compliance.
- Prone positioning significantly improved oxygenation (Pao2/FiO2 ratio) and lung compliance within 24 hours.
- 90-day survival rates were similar between prone and supine groups (93% vs 96%).
Conclusions:
- Prone positioning significantly enhances lung compliance and oxygenation post-lung transplantation.
- Further prospective studies are required to confirm these benefits.
