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Segmental Collagenoma in Tuberous Sclerosis - Think Beyond the Skin: A Rare Case Report
Ashok Kumar Nagarajan1, Krishnaswamy Manoharan1, Shreya Moozhiyil1
1Department of DVL, Sree Balaji Medical College and Hospital, Chromepet, Chennai, Tamil Nadu, India.
Abstract:
Collagenomas are connective tissue nevi characterized by an imbalance in the distribution and amount of collagen in the extracellular matrix. Shagreen patch, a collagenoma of tuberous sclerosis, is a classical finding in this genodermatosis (Tuberous Sclerosis). Though the prototypical lesion is a shagreen patch, some individuals manifest only small collagenomas, and these can hinder a diagnosis of tuberous sclerosis and thus mask underlying systemic involvement as was seen in this case we have reported, wherein a 22-year-old male presented with segmental collagenomas over the face and calcified subependymal nodules of the brain on further investigation.
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