Risk factors for multiple recurrent ischemic strokes
Nevzat Uzuner1, Gulnur Tekgol Uzuner1
1Department of Neurology, Eskisehir Osmangazi University, Turkey.
Insights
Patients with congestive heart disease and diabetes mellitus face higher risks of multiple recurrent ischemic strokes. This highlights the need for intensified management strategies post-stroke.
Area of Science:
- Neurology
- Cardiology
- Epidemiology
Background:
- Recurrent ischemic stroke is a significant concern, influenced by modifiable risk factors like cardiovascular diseases, hypertension, diabetes mellitus, dyslipidemia, and atrial fibrillation.
- Identifying predictors for multiple stroke recurrences is crucial for improving patient outcomes.
Purpose of the Study:
- To investigate the risk factors associated with experiencing more than two recurrent ischemic strokes following a first-ever stroke.
Main Methods:
- A cohort of 927 ischemic stroke patients was retrospectively analyzed from a stroke registry.
- Patients were followed for recurrent ischemic stroke over a 9-year period (post-2008).
Main Results:
- 20% of patients experienced at least one recurrent ischemic stroke, with 3.5% having multiple recurrences.
- The mean time to first recurrence was 1 year, and to multiple recurrences was 3 years.
- Congestive heart disease (P < 0.015) and diabetes mellitus (P < 0.006) were identified as significant risk factors for multiple recurrences.
Conclusions:
- Congestive heart disease and diabetes mellitus are associated with a higher incidence of multiple ischemic stroke recurrences, even with optimal treatment.
- Enhanced monitoring and targeted interventions for these patient groups are warranted to mitigate recurrent stroke risk.
Background:
Cardiovascular diseases, hypertension, diabetes mellitus, dyslipidemia, and atrial fibrillation are the most common modifiable risk factors for recurrent ischemic stroke. In this study, we aimed to find the risk factors associated with more than two recurrent ischemic strokes after the first-ever stroke.
Methods:
We collected the ischemic stroke patients in our stroke registry data bank, and the eligible patients were followed for recurrent ischemic stroke after 2008. Our study consisted of 927 patients who were followed up for 9 years after the first-ever stroke.
Results:
We found that 185 (20%) patients had a recurrent ischemic stroke, and another 32 (3.5%) patients had more than one recurrence after the first-ever ischemic stroke. The mean time for the first stroke recurrence was 1 year, and the mean time for the multiple stroke recurrences was 3 years. Significant risk factors for multiple recurrences were congestive heart disease (P < 0.015) and diabetes mellitus (P < 0.006).
Conclusions:
We concluded that even with the appropriate treatments, patients with congestive heart disease and diabetes mellitus have a higher rate of multiple recurrences for ischemic stroke after the first-ever ischemic stroke, indicating that more attention should be paid to this issue.
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