A Ukrainian infant with giant coronary aneurysms: A case report and literature review
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Published on: September 8, 2023
Yuliia Klymyshyn1, Oleksii Datsko1, Yuriy Stepanovskyy2,3
1Department of Cardiology Ukrainian Children's Cardiac Center Kyiv Ukraine.
Insights
Differentiating between Kawasaki disease (KD) and multisystem inflammatory syndrome in children (MIS-C) is challenging. Prompt immunomodulatory treatment is crucial for both conditions to prevent coronary artery aneurysms, even before a definitive diagnosis.
Area of Science:
- Pediatric Cardiology
- Infectious Diseases
- Immunology
Background:
- COVID-19 can cause multisystem inflammatory syndrome in children (MIS-C).
- MIS-C presents symptoms that closely mimic Kawasaki disease (KD).
- Both KD and MIS-C pose a risk of developing coronary artery aneurysms.
Key Clinical Message:
COVID may manifest multisystem inflammatory syndrome in children (MIS-C) which mimics Kawasaki disease (KD). Differentiating KD and MIS-C is difficult. Immunomodulatory treatment should be initiated promptly without accurate diagnosis.
Abstract:
A febrile Ukrainian infant developed giant aneurysms in coronary arteries. Differentiating between Kawasaki disease and multisystem inflammatory syndrome in children was difficult. In both illnesses, coronary aneurysm may develop unless treated promptly. Therefore, guidelines should synthesize these clinical entities so that treatment can be initiated before rigorous diagnosis.
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