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PREDICTORS OF MULTIFOCAL PAPILLARY THYROID CANCER. DO THEY EXIST?
O V Mazur1, V A Palamarchuk1, O A Tovkai1
1Ukrainian Scientific and Practical Center of Endocrine Surgery, Transplantation of Endocrine Organs and Tissues of the Ministry of Health of Ukraine.
Acta Endocrinologica (Bucharest, Romania : 2005)
|May 8, 2023
Summary
Identifying predictors for multifocal papillary thyroid carcinoma (PTC) remains challenging. Fibrous changes in the thyroid may indicate additional PTC lesions, suggesting a need for improved ultrasound and focus on unifocal PTC in specific cases.
Area of Science:
- Endocrinology
- Oncology
- Radiology
Background:
- Multifocal papillary thyroid carcinoma (PTC) presents diagnostic challenges.
- Predicting multifocal growth is crucial for effective treatment planning.
Purpose of the Study:
- To identify key predictors of multifocal papillary thyroid carcinoma (PTC).
- To analyze risk factors associated with additional PTC lesions.
Main Methods:
- Comparative analysis of patients with multifocal (n=109) and unifocal (n=50) PTC.
- Inclusion of patients with T1-3mN0Mx and T1-T3N0Mx categories undergoing thyroidectomy with lymphadenectomy.
- Evaluation of ultrasound characteristics and thyroid gland tissue changes.
Main Results:
- Fibrous changes in the thyroid gland are identified as a potential risk factor for additional PTC lesions.
- No definitive predictors for multifocal PTC growth were unequivocally established.
Conclusions:
- Clear predictors for multifocal PTC growth are not yet identified.
- Enhanced ultrasound quality is recommended.
- Focusing on unifocal PTC in patients with thyroid gland fibrinous changes and normal TSH levels is advisable.
