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Author Spotlight: Exploring the Relationship Between Lipotoxicity and HFpEF
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Factors associated with lipid control in outpatients with heart failure

Anan S Jarab1,2, Walid Al-Qerem3, Hanan Hamam1

  • 1Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan.

Frontiers in Cardiovascular Medicine
|May 8, 2023
PubMed

Insights

Most heart failure patients have poor lipid control, a condition linked to uncontrolled blood pressure, higher hemoglobin, and elevated white blood cell counts. Improving blood pressure management is key to better outcomes for these patients.

Area of Science:

  • Cardiology
  • Endocrinology
  • Public Health

Background:

  • Dyslipidemia is prevalent in heart failure (HF) patients, adversely affecting clinical outcomes.
  • Limited data exists on factors contributing to poor lipid control in HF populations.
  • This study addresses the need for understanding lipid management challenges in HF.

Purpose of the Study:

  • To evaluate lipid control status in heart failure patients.
  • To identify factors associated with poor lipid control in this cohort.
  • To inform targeted interventions for improved patient outcomes.

Main Methods:

  • A cross-sectional study conducted in Jordanian outpatient cardiology clinics.
  • Data collected via medical records and questionnaires, including socio-demographics, biomedical variables, and disease/medication characteristics.
  • Binary logistic regression used to determine predictors of poor lipid control, with medication adherence assessed using the 4-item Medication Adherence Scale.

Main Results:

  • 78% of 428 heart failure patients exhibited poor lipid control.
  • Uncontrolled blood pressure (BP) was associated with poor lipid control (OR=0.552).
  • Higher hemoglobin (Hb) levels (OR=1.178) and elevated white blood cell (WBC) counts (OR=1.133) were also linked to poor lipid control.

Conclusions:

  • A significant proportion of heart failure patients suffer from poor lipid control.
  • Intervention strategies should prioritize blood pressure management to enhance health outcomes.
  • Addressing dyslipidemia through BP control may improve overall prognosis in HF patients.
Abstract

Keywords:
cardiovascular diseasefactorsheart failureinterventionslipid control

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