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Massive true thymic hyperplasia with osseous metaplasia
Jun Kanzawa1, Mitsuru Matsuki2, Shintaro Kano1
1Department of Radiology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke-shi, Tochigi-ken, 329-0498, Japan.
Radiology Case Reports
|May 8, 2023
Summary
Massive true thymic hyperplasia, a rare condition, involves enlarged thymus causing symptoms. This case highlights unique imaging findings, including osseous metaplasia, in a child.
Area of Science:
- Medical Imaging
- Pathology
- Pediatric Radiology
Background:
- True thymic hyperplasia (TTH) is characterized by increased thymic size and weight with normal histology.
- Massive TTH is rare and can cause symptoms due to compression of adjacent structures.
- Imaging findings of massive TTH are not well-documented.
Observation:
- A case of massive TTH in a 3-year-old girl is presented.
- Contrast-enhanced CT showed a bilobed anterior mediastinal mass.
- The mass contained punctate and linear calcifications within curvilinear septa.
Findings:
- The calcifications represented lamellar bone deposits, indicating osseous metaplasia.
- This is the first reported case of massive TTH with osseous metaplasia.
- Imaging features of this rare condition were detailed.
Implications:
- This case expands the understanding of TTH imaging manifestations.
- It highlights the importance of recognizing osseous metaplasia in thymic masses.
- Further research into the etiology of TTH with osseous metaplasia is warranted.
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