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Updated: Jul 31, 2025

Enhanced Yeast One-hybrid Screens To Identify Transcription Factor Binding To Human DNA Sequences
Published on: February 11, 2019
CREPE: a Shiny app for transcription factor cataloguing
Diego A Rosado-Tristani1, José A Rodríguez-Martínez1
1Department of Biology, University of Puerto Rico Río Piedras, San Juan 00925, Puerto Rico.
Summary:
Transcription factors (TFs) are proteins that directly interpret the genome to regulate gene expression and determine cellular phenotypes. TF identification is a common first step in unraveling gene regulatory networks. We present CREPE, an R Shiny app to catalogue and annotate TFs. CREPE was benchmarked against curated human TF datasets. Next, we use CREPE to explore the TF repertoires of Heliconius erato and Heliconius melpomene butterflies.
Availability And Implementation:
CREPE is available as a Shiny app package available at GitHub (github.com/dirostri/CREPE).
Supplementary Information:
Supplementary data are available at Bioinformatics Advances online.
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