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Updated: Jul 31, 2025

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
07:25

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Stranger Things: New Roles and Opportunities for Androgen Receptor in Oncology Beyond Prostate Cancer

Javier Leo1,2, Eleonora Dondossola3, Kaitlin J Basham4

  • 1Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.

Endocrinology
|May 8, 2023
PubMed

Insights

The androgen receptor (AR) is crucial in prostate cancer treatment. Emerging research reveals AR

Area of Science:

  • Oncology
  • Molecular Biology
  • Drug Discovery

Background:

  • The androgen receptor (AR) is a well-established therapeutic target in oncology.
  • AR signaling is central to prostate cancer cell biology and treatment strategies.
  • Current treatments for advanced prostate cancer heavily rely on AR modulation.

Conclusions:

  • The androgen receptor (AR) presents a promising therapeutic target in multiple cancer types.
  • Understanding AR's expanded roles can guide the development of novel treatment strategies.
  • Targeting AR offers new avenues for oncological therapies.
Keywords:
adrenal cancerandrogen receptorbladder cancerbreast cancerendometrial cancerliver cancermelanomaprostate cancer

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