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Updated: Jul 31, 2025

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs
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Fatal granulomatous amebic encephalitis initially presenting with a cutaneous lesion

Prudence E Gramp1, John Dooley2, Blake O'Brien3

  • 1Dermatology Department, Gold Coast University Hospital, Gold Coast, Queensland, Australia.

The Australasian Journal of Dermatology
|May 8, 2023
PubMed

Insights

A rare Balamuthia mandrillaris infection caused a skin lesion that progressed to fatal granulomatous amoebic encephalitis in a 66-year-old man. This case highlights the importance of PCR for diagnosing this devastating condition.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Neurology

Background:

  • Balamuthia mandrillaris is an opportunistic protozoan pathogen.
  • Cutaneous Balamuthia infections can progress to granulomatous amoebic encephalitis (GAE).
  • GAE is a rare but highly fatal central nervous system infection.
Keywords:
Balamuthia mandrillarisAmebiasisBalamuthia mandrillaris CNS infectionamebicinfectious encephalitismeningoencephalitis

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