Related Experiment Video
Updated: Aug 25, 2026

The Supraclavicular Fossa Ultrasound View for Central Venous Catheter Placement and Catheter Change Over Guidewire
Published on: December 23, 2014
[Venous thrombosis in central venous catheterization: incidence and promoting factors]
Insights
Central vein catheterization can lead to venous thrombosis, with upper limb insertion sites posing the highest risk. Alternative insertion methods, like jugular or subclavian veins, may reduce thrombosis risk but carry their own complications.
Area of Science:
- Vascular Surgery
- Medical Devices
- Thrombosis Research
Background:
- Central venous catheters are essential for patient care but associated with risks.
- Venous thrombosis is a significant complication of central venous catheterization.
- Identifying risk factors is crucial for patient safety.
Purpose of the Study:
- To prospectively investigate the incidence of venous thrombosis.
- To identify risk factors associated with central venous catheterization.
- To evaluate the safety of different catheter insertion sites.
Main Methods:
- Prospective study of 51 patients undergoing 53 central venous catheterizations.
- Phlebography used to diagnose venous thrombosis.
- Analysis of potential risk factors including insertion site and infusate properties.
Main Results:
- A 23% thrombosis rate was observed (12 out of 53 catheterizations).
- Upper limb insertion sites were implicated in 11 of the 12 thrombosis cases.
- No significant association found with fluid osmolality or catheter length.
Conclusions:
- Upper limb venous catheterization is a significant risk factor for thrombosis.
- Jugular or subclavian vein insertion may be preferable to reduce thrombosis risk.
- All central venous catheterization routes require careful consideration of potential complications.
Abstract:
The frequency of venous thrombosis during central vein catheterization was prospectively studied in a group of 51 patients (53 catheterizations) during a 10-month period. 12 catheterizations (23%) resulted in thrombosis as revealed by phlebography. Of these, 11 were due to catheters whose site of entry was the upper limb. No other favoring factors (osmolality of the infused fluids, length or catheterization etc.) were detected. Ideally, to avoid thrombosis, central venous catheters should be inserted via the jugular or the subclavian vein, while bearing in mind that these other routes are not devoid of complications either.
Related Concept Videos
Venous Return
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system as it...
Varicose Veins I: Introduction
Venous Thrombosis I: Introduction
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Venous Thrombosis III: Interprofessional Care
Venous Thrombosis IV: Nursing Management

