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Updated: Jul 31, 2025

Behavioral Assessment of Hearing in 2 to 4 Year-old Children: A Two-interval, Observer-based Procedure Using Conditioned Play-based Responses
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Behavioral Assessment of Hearing in 2 to 4 Year-old Children: A Two-interval, Observer-based Procedure Using Conditioned Play-based Responses

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Referral rate and false-positive rates in a hearing screening program among high-risk newborns

Kruthika Thangavelu1, Kyriakos Martakis2,3, Silke Feldmann4

  • 1Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Marburg, Philipps-Universität Marburg, Baldingerstrasse, 35043, Marburg, Germany. Kruthika.thangavelu@uk-gm.de.

European Archives of Oto-Rhino-Laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
|May 8, 2023
PubMed

Insights

False-positive results in newborn hearing screening are linked to prematurity and low birth weight. Higher infant age at screening also increases false-positives, impacting program effectiveness.

Area of Science:

  • Neonatal care
  • Audiology
  • Public health

Background:

  • Newborn hearing screening is crucial for early detection of hearing loss.
  • Improving the accuracy and cost-effectiveness of screening programs is essential.
  • Understanding factors influencing false-positive results can optimize screening protocols.

Purpose of the Study:

  • To determine referral and false-positive rates in a high-risk newborn hearing screening program.
  • To identify factors associated with false-positive results in auditory brainstem response (ABR) screening.

Main Methods:

  • Retrospective cohort study of 4512 newborns undergoing a two-stage AABR screening protocol.
  • Analysis of referral rates, false-positive rates, and potential risk factors.
  • Statistical analysis to assess associations between infant characteristics and false-positivity.

Main Results:

  • The overall referral rate was 3.8%, with a false-positive rate of 2.9%.
  • Higher birth weight and gestational age were associated with lower odds of false-positive results.
  • Increased chronological age at screening correlated with higher odds of false-positive results.

Conclusions:

  • Prematurity and low birth weight are significant contributors to false-positive hearing screening results in high-risk infants.
  • Chronological age at the time of screening is a key factor influencing false-positive rates.
  • These findings can inform strategies to enhance the efficiency of newborn hearing screening.
Abstract

Keywords:
AABRFalse-positivityHearing screeningHigh-risk newbornsNewborn

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