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Updated: Jul 31, 2025

Induction and Validation of Cellular Senescence in Primary Human Cells
Published on: June 20, 2018
Developing Sustainable Cancer and Aging Programs
Tina Hsu1, Rawad Elias2,3, Kristine Swartz4
1The Ottawa Hospital Cancer Centre, University of Ottawa, Ottawa, ON, Canada.
Abstract:
Geriatric assessment (GA) has been shown to decrease toxicity from systemic therapy, improve completion of chemotherapy, and reduce hospitalizations in older adults with cancer. Given the aging of the cancer population, this has the potential to have a positive impact on the care of a large swath of patients seen. Despite endorsement by several international societies, including the American Society of Clinical Oncology, uptake of GA has been low. Lack of knowledge, time, and resources has been cited as reasons for this. Although challenges to developing and implementing a cancer and aging program vary depending on the health care context, GA is adaptable to every health care context from low- to high-resource settings, as well as those in which geriatric oncology is a well-established or just emerging field. We provide an approach for clinicians and administrators to develop, implement, and sustain aging and cancer programs in a doable and sustainable way.
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