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Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
Published on: September 25, 2019
Clinical Reasoning: A 67-Year-Old Man With Multiple Intracranial Lesions
Angeline Ngo1, Kevin McGehrin2, Christina Di Loreto2
1From the Department of Neurosciences (A.N., K.M., J.N.L.), University of California San Diego; Office of the Coroner Ada County (C.D.L.), Boise, ID; and Department of Neurology (R.A.), Keck School of Medicine of USC, Los Angeles, CA. ann011@health.ucsd.edu.
This case report details a patient with multiple intracranial lesions whose condition initially improved with steroids and antibiotics but recurred, highlighting diagnostic challenges for undifferentiated brain pathology.
Area of Science:
- Neurology
- Radiology
- Pathology
Background:
- Intracranial lesions can manifest from diverse pathologies.
- Undifferentiated intracranial pathology presents diagnostic challenges.
Observation:
- A 67-year-old man presented with nausea, headache, and ataxia, revealing multiple intracranial lesions.
- Initial treatment with steroids and antibiotics led to symptom improvement.
- Symptoms recurred after 3 months, with MRI showing lesion progression.
Findings:
- Diagnostic workup for the intracranial lesions was initially unrevealing.
- The case underscores the importance of a systematic diagnostic approach.
- A definitive diagnosis was eventually established, prompting further discussion.
Implications:
- This case provides insights into managing patients with undiagnosed intracranial lesions.
- It emphasizes the need for reassessment when symptoms recur.
- The report contributes to understanding the diagnostic pathway for complex neurological presentations.
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