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Updated: Jul 31, 2025

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Forkhead box protein D2 suppresses colorectal cancer by reprogramming enhancer interactions

Hyo-Min Kim1, Byunghee Kang1, Sohyun Park1

  • 1Department of Life Sciences, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea.

Nucleic Acids Research
|May 9, 2023
PubMed
Summary

Forkhead box protein D2 (FOXD2) suppresses colorectal cancer by regulating gene expression in intestinal stem cells. Overexpression of FOXD2 rewires chromatin interactions, promoting apoptosis and potentially offering a new therapeutic target.

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