Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Teeth01:15

Teeth

519
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
519
Tooth Anatomy01:21

Tooth Anatomy

594
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
594
Minerals01:26

Minerals

368
Minerals are essential nutrients that the human body needs in small amounts to work properly. They play a vital role in many bodily functions, such as building strong bones and transmitting nerve impulses. Some minerals are needed for hormone production or to maintain a normal heartbeat. Major minerals include calcium, phosphorus, potassium, sulfur, sodium, chlorine, and magnesium, while trace minerals include iron, manganese, copper, iodine, zinc, cobalt, fluoride, and selenium.
 
Major...
368
Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

4.2K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
4.2K
Bone Disorders01:29

Bone Disorders

3.7K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.7K
Inborn Errors of Metabolism01:20

Inborn Errors of Metabolism

207
Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...
207

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Achieving Optimal Esthetic Outcome With Previously Placed, Compromised Implants.

Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995)·2019
Same author

Understanding the esthetic evaluation for success.

Journal of the California Dental Association·2004
See all related articles

Related Experiment Video

Updated: Jul 31, 2025

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
08:12

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants

Published on: March 29, 2018

10.2K

Amelogenesis imperfecta: More than just an enamel problem.

Tal Morr1

  • 1TM Prosthodontics, Restorative Dentistry Esthetics, and Implant Dentistry, Miami, Florida, USA.

Journal of Esthetic and Restorative Dentistry : Official Publication of the American Academy of Esthetic Dentistry ... [Et Al.]
|May 9, 2023
PubMed
Summary

Amelogenesis imperfecta (AI) is a rare genetic disorder affecting tooth enamel formation. Early diagnosis and a phased orthodontic and prosthodontic treatment approach are crucial for managing AI's complex dental and aesthetic challenges.

Keywords:
amelogenesis imperfectaankyloglossiaanterior open biteroot proximitysmall teeth

More Related Videos

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface
08:26

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface

Published on: July 10, 2014

15.1K
Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
07:26

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology

Published on: August 22, 2022

1.5K

Related Experiment Videos

Last Updated: Jul 31, 2025

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
08:12

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants

Published on: March 29, 2018

10.2K
Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface
08:26

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface

Published on: July 10, 2014

15.1K
Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
07:26

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology

Published on: August 22, 2022

1.5K

Area of Science:

  • Dental Science
  • Genetics
  • Oral Health

Background:

  • Amelogenesis imperfecta (AI) is a group of inherited disorders affecting enamel development.
  • AI can manifest with diverse clinical presentations, including enamel hypoplasia, hypocalcification, and hypomaturation.
  • This article focuses on the hypoplastic form (Type I) of AI.

Observation:

  • Patients with AI exhibit abnormal enamel formation, potentially leading to aesthetic concerns and functional deficits.
  • Associated dental anomalies may include vertical dysgnathia, anterior open bite, and posterior crossbite.
  • A case report illustrates a comprehensive treatment strategy from mixed to permanent dentition.

Findings:

  • The study outlines the clinical presentation and various treatment considerations for AI.
  • It emphasizes the importance of a sequenced treatment plan involving both orthodontic and prosthodontic interventions.
  • Successful management requires a multidisciplinary approach tailored to the individual patient's needs.

Implications:

  • Early intervention in AI management is critical for optimizing long-term oral health and function.
  • Addressing AI can significantly improve patients' aesthetics, self-esteem, and overall quality of life.
  • This approach provides a framework for managing complex AI cases, ensuring functional and aesthetic restoration.