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Updated: Jul 31, 2025

Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research
Published on: January 22, 2011
OncoCardioDB: a public and curated database of molecular information in onco-cardiology/cardio-oncology
Angela L Riffo-Campos1,2, Juan Domingo2, Esther Dura2
1Millennium Nucleus on Sociomedicine (SocioMed), Universidad de La Frontera, Doctorado en Ciencias Médicas, C/Francisco Salazar, 1145 Temuco, Chile.
Abstract:
Numerous studies have been published which, separately, investigate the influence of molecular features on oncological and cardiac pathologies. Nevertheless, the relationship between both families of diseases at the molecular level is an emerging area within onco-cardiology/cardio-oncology. This paper presents a new open-source database that aims to organize the curated information concerning the molecular features validated in patients involved in both cancer and cardiovascular diseases. Entities like gene, variation, drug, study and others are modelled as objects of a database which is populated with curated information from 83 papers identified by systematic literature searched for up to 2021. Researchers will discover new connections among them to validate hypotheses or suggest new ones. Special care has been taken to use standard nomenclature for genes, pathologies and all the objects for which accepted conventions exist. The database can be consulted via the web with a system of simplified queries, but it also accepts any query. It will be updated and refined with the incorporation of new studies as they become available. Database URL http://biodb.uv.es/oncocardio/.
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