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Related Concept Videos

Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

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Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
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Synteny and Evolution02:31

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John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
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Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
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Comparing Copy Number Variations and SNPs02:26

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Sequencing of the human genome has opened up several best-kept secrets of the genome. Scientists have identified thousands of genome variations that exist within a population. These variations can be a single nucleotide or a larger chromosomal variation.
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Genomics02:02

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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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The present-day mitochondrial and chloroplast genomes have retained some of the characteristics of their ancestral prokaryotes and also have acquired new attributes during their evolution within eukaryotic cells. Like prokaryotic genomes, mitochondrial and chloroplast genomes neither bind with histone-like proteins nor show complex packaging into chromosome-like structures, as observed in eukaryotes. Unlike mitotic cell divisions observed in eukaryotic cells, mitochondria and chloroplasts...
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Updated: Jul 31, 2025

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SyntenyViewer: a comparative genomics-driven translational research tool.

Raphael Flores1,2, Cécile Huneau3, Laura Burlot1

  • 1Université Paris-Saclay, INRAE, URGI, Versailles 78026, France.

Database : the Journal of Biological Databases and Curation
|May 9, 2023
PubMed
Summary

SyntenyViewer offers comparative genomics data for flowering plants, enabling evolutionary studies and translational research by cataloging conserved genes and tracking genomic changes across species.

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Area of Science:

  • Genomics
  • Evolutionary Biology
  • Bioinformatics

Background:

  • Comparative genomics is crucial for understanding plant evolution and gene function.
  • A comprehensive database of conserved genes across angiosperm species is needed for both research and applied agriculture.

Purpose of the Study:

  • To introduce SyntenyViewer, a web-based tool for comparative genomics in angiosperms.
  • To provide a resource for studying gene conservation, evolutionary dynamics, and translational research.

Main Methods:

  • Development of a relational database containing comparative genomics data.
  • Analysis of gene conservation and genomic rearrangements across 44 angiosperm species and inferred ancestral genomes.

Main Results:

  • SyntenyViewer provides comparative genomics data for seven major botanical families.
  • A catalog of 103,465 conserved genes has been established, detailing evolutionary events like duplications and inversions.
  • The tool facilitates translational research by identifying key trait-related genes.

Conclusions:

  • SyntenyViewer is a valuable public resource for fundamental evolutionary studies and applied translational research in flowering plants.
  • The platform supports the investigation of gene and genome evolution and enables the transfer of knowledge from model species to crops.