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Updated: Jul 31, 2025
07:15
Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
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Factors Associated with Periodontitis in Patients with and without HIV
Luanderson Lopes Pereira1, Daniele Veiga Siqueira Amorim1, Willian Brito Sampaio1
1Postgraduate Program in Dentistry and Health, Federal University of Bahia (UFBA), Salvador, Brazil.
International Journal of Dentistry
|May 9, 2023
Summary
People living with HIV, particularly older individuals, have a higher prevalence of periodontitis. Certain antiretroviral therapies, like nonnucleoside reverse transcriptase inhibitors, may also increase risk.
Area of Science:
- Oral health research
- Infectious disease epidemiology
Background:
- Periodontitis is a common oral condition.
- HIV infection can impact immune function and potentially oral health.
- Highly Active Antiretroviral Therapy (HAART) has transformed HIV management.
Purpose of the Study:
- To compare periodontal health between HIV-positive individuals on HAART and HIV-negative individuals.
- To identify factors associated with periodontitis in both groups.
Main Methods:
- Cross-sectional study design.
- Clinical oral examinations for periodontitis diagnosis.
- Questionnaires for personal, habit, and hygiene data.
- Logistic regression for multivariate analysis.
Main Results:
- Individuals with HIV, especially those over 43, showed increased odds of moderate to severe periodontitis.
- Among HIV-positive individuals, advanced age and use of nonnucleoside reverse transcriptase inhibitors (NNRTIs) were associated with higher periodontitis risk.
Conclusions:
- A higher prevalence of periodontitis was observed in people living with HIV.
- Advanced age and HIV infection are associated with moderate to severe periodontitis.
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